ADAP drugs: clotrimazole

clotrimazole
(Gyne-Lotrimin, Lotrimin, Mycelex)

Drug description

Clotrimazole ointment is used to topically treat vaginal candidiasis and candida of the scrotum and anus. Clotrimazole is also used for candida infections like jock itch and athlete’s foot, and to treat thrush infections of the esophagus and mouth.

Side effects
No side effects with topical treatment. Occasional side effects of oral medication are nausea, dizziness, diarrhea, and change in liver function. Clotrimazole has been used in second and third trimesters of pregnancy without adverse effects.

Dosage
Clotrimazole comes in lozenge, topical cream and solution formulas, as well as over-the-counter vaginal cream and tablet form. Clotrimazole is the most common topical treatment for thrush. A 1% solution is applied twice daily. Clotrimazole comes in 10 mg lozenges that are held in the mouth until they dissolve, 5 times daily. For vaginal fungal infection, 100 mg tablets daily for 7 days or 200 mg for 3 days (non-pregnant only) are prescribed. If the infection is uncomplicated, you may be treated with one 500 mg dose, or 5 g of 1% vaginal cream daily for 7-14 days. Vaginal preparations should be used at bedtime for maximum contact with mucous membranes. If you miss a dose, do not double doses.

How long it may take to work
You should experience a decrease in skin irritation and discomfort, followed by a clearing of the infection. Length of time to improve depends on the organism and site of infection.

Managing side effects
Change clothing in contact with the infected area after each application. Use sanitary napkins to prevent staining of clothing or bedding. Lie down for at least 30 minutes following vaginal treatment. The medication may cause minor skin irritation in your sexual partner. Either refrain from sex during treatment or have your partner use a condom.

This information is specific to the use of this medication for HIV-related conditions. For additional information about this drug for other conditions, refer to: www.nursespdr.com/ and www.healthanswers.com/Library/library_fset.asp

The drug descriptions on these pages are intended for informational purposes only. The Network does not promote or endorse the use of any specific treatment for any health-related condition. The medications described here can only be dispensed by a licensed health care professional. The information may have changed since these pages were updated, though every effort is made to keep these pages current. Please contact The Network at (800) 734-7104 to make sure you have the most up-to-date information

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